Windows Registry Editor Version 5.00

; or via PsExec -accepteula -s reg add "HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows Defender" /f /v DisableAntiSpyware /t REG_DWORD /d 00000001
[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows Defender]
"DisableAntiSpyware"=dword:00000001